Bless meaning : To make something holy by religious rite, sanctify. To make the sign of the cross upon, so as to sanctify. To invoke divine favor upon. To honor as holy, glorify; to extol for excellence. To esteem or account happy; to felicitate. To wave; to brandish. (past tense only blessed) To turn (a reference) into an object. (with from) To secure, defend, or prevent from.