Depressions meaning : In psychotherapy and psychiatry, a state of mind producing serious, long-term lowering of enjoyment of life or inability to visualize a happy future. An area that is lower in topography than its surroundings. In psychotherapy and psychiatry, a period of unhappiness or low morale which lasts longer than several weeks and may include ideation of self-inflicted injury or suicide. An area of lowered air pressure that generally brings moist weather, sometimes promoting hurricanes and tornadoes. A period of major economic contraction. Four consecutive quarters of negative, real GDP growth. See NBER. The act of lowering or pressing something down. A lowering, in particular a reduction in a particular biological variable or the function of an organ, in contrast to elevation.