Isolation meaning : The state of being isolated, detached, or separated. The state of being away from other people. The act of isolating. (of a country) The state of not having diplomatic relations with other countries (either with most or all other countries, or with specified other countries). The obtaining of an element from one of its compounds, or of a compound from a mixture The separation of a patient, suffering from a contagious disease, from contact with others (compare: quarantine) A database property that determines when and how changes made in one transaction are visible to other concurrent transactions.