Mollies meaning : Any of many New World fish of the genus Poecilia, formerly called Mollienesia. A Molotov cocktail. A woman or girl, especially of low status. An effeminate male, a male homosexual. Pure MDMA powder. A mollemoke. A female cat, a she-cat (usually spayed) A bird, the wagtail. A molly bolt. To engage in (male) homosexual activity with. A fish of the genus Poecilia, except for those known as guppies.