Muddles meaning : A mixture; a confusion; a garble. A mixture of crushed ingredients, as prepared with a muddler. To mix together, to mix up; to confuse. To mash slightly for use in a cocktail. To dabble in mud. To make turbid or muddy. To think and act in a confused, aimless way. To cloud or stupefy; to render stupid with liquor; to intoxicate partially. To waste or misuse, as one does who is stupid or intoxicated.